Knowledge & Professional Insights
Evidence-based publications and professional analysis in transfusion medicine.
Knowledge Development in Transfusion Practice
We are dedicated to the continuous advancement of knowledge in blood banking. Our journal features technical papers and professional reviews on operational methodologies and evidence-based transfusion practices.
Compatibility Testing (Pre-Transfusion Testing)
Procedural overview of pre-transfusion testing including ABO/Rh grouping, antibody screening, phenotyping and crossmatching workflow.
The Immediate Spin Crossmatch: Principles and Methodology
Technical overview of the Immediate Spin Crossmatch (ISXM), a rapid serologic compatibility test used to detect ABO incompatibility between donor red cells and recipient serum. The paper explains immunohematologic principles, standardized methodology, interpretation criteria, and clinical limitations within modern type-and-screen transfusion protocols.
Crossmatch Methodologies in Transfusion Medicine
Comprehensive technical review of major crossmatching methodologies used in transfusion medicine including Immediate Spin, Bovine Albumin, LISS, Gel Column Agglutination Technology (CAT), and PEG-enhanced antiglobulin testing. The paper explains the immunohematologic principles, reaction mechanisms, sensitivity characteristics, and clinical applications of each technique in modern compatibility testing workflows.
Quality Measures in Transfusion Transmitted Infection (TTI) Screening
Technical overview of quality assurance practices in transfusion transmitted infection (TTI) screening laboratories including mandatory testing protocols, serological and NAT methods, internal and external quality control, Levey–Jennings monitoring, Westgard rule application, documentation systems, and root cause analysis for error management.
Eligibility Criteria for Blood Donation
Technical overview of donor eligibility criteria for blood donation based on national transfusion guidelines and WHO voluntary donation principles. The paper outlines donor health requirements, medical history screening, infection risk assessment, vaccination and medication deferrals, and operational safeguards designed to ensure both donor safety and transfusion recipient protection.
Confirmation of Bombay and Para-Bombay Blood Group
Technical overview of laboratory procedures used to confirm the Bombay (Oh) and Para-Bombay blood group phenotypes. The paper describes diagnostic discrepancies during routine ABO grouping, specialized serological tests such as Anti-H lectin testing, saliva secretor testing, adsorption–elution studies, and molecular confirmation through FUT1 and FUT2 gene analysis to accurately distinguish these rare phenotypes from the common O blood group.